Controlled, Randomized Chronotherapeutic Lifestyle Intervention Studies in Night Shift Workers

Implementation of short-term chronotherapeutic lifestyle interventions (timed exercise, melatonin intake and light exposure) in newly designed, intensely phenotyped night shift workers cohorts in U.K., Austria, Germany, and Italy to prove the causal relationship between disruption of the circadian clocks and lifestyle intervention.

The goal is to build a database that will allow us to identify whether interventions through timed exercise, light exposure or melatonin improve circadian rhythms and metabolic control in night shift workers.